CBD may help with Osteoporosis

This information is a bit technical when it comes to canabinoids and the skeletal system but I really wanted to find out if CBD may help with Osteoporosis. It takes a lot of time and one can get into a bit of a fix if you move too fast. This I’ve learned from the past, so I felt it best to rather give you more than less. This way you can choose how deep you want to go.

Endocannabinoids control basic biological processes including cell choice between survival and death and progenitor/stem cell proliferation and differentiation.

Basically a high percentage of canabinoid receptors are present in the skeletal sympathetic nerve terminals..

They regulate and facilitate bone formation and it is discovered that a specific canabinoid CB2 is the main component associated with maintaining bone remodeling

They are found to regulate and facilitate bone formation. It is discovered that a specific canabinoid CB2 is the main component associated with maintaining bone remodeling and keeping it at balance. Thus also protects the skeletal structure against age-related bone loss.
“Since the discovery of the endocannabinoid system, its presence and involvement have been reported in a handful of biological systems. Recently, the skeleton has been identified as a major endocannabinoid target through both the neuronal CB1 and predominantly peripheral CB2 cannabinoid receptors. CB1 is present in sympathetic nerve terminals in bone, whereas CB2 is expressed in osteoblasts and osteoclasts, the respective bone-forming and -resorbing cells.”

Furthermore, the skeleton appears as the main system physiologically regulated by CB2.

“CB2-deficient mice show a markedly accelerated age-related bone loss. The CB2 locus in women is associated with low bone density and osteoporotic fractures. Since activation of CB2 attenuates experimentally induced bone loss by inhibiting bone resorption and stimulating bone formation, and because synthetic cannabinoids are stable and orally available, a therapy based on synthetic CB2 agonists is a promising novel target for antiosteoporotic drug development.”

It appears that the main physiologic involvement of CB2 is associated with maintaining bone remodeling at balance, thus protecting the skeleton against age-related bone loss.

Lots of scientific words there but I’m sure you’ve got the idea.
If you like you can study it further on PubMed here: https://www.ncbi.nlm.nih.gov/pubmed/17646266

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Meduca cannabinoid supplement contains CBD that may help with Osteoporosis
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This is important because Cannabinoids are not present in our modern diet & most people are not even aware that they need them nutritionally. Through providing you with a high potency, natural, non-toxic & safe daily boost of non-psychoactive Hemp-Cannabinoids, Canamere can help you support the most powerful system that your body possesses for wellbeing. Improve your family’s life and wellbeing by supporting the endocannabinoid system with Meduca™.

DISCLAIMER: 4 WAC is an independent distributor for Canamere. Both 4 WAC and Canamere neither agrees nor disagrees, and does not support, endorse or substantiate any claims or indications made in these external references. We only provide it here for educational purposes for those that are interested in learning more. We invite you to do your own research remembering that Canamere’s product is not a drug & is not intended to diagnose, cure, prevent or treat any disease. 4WAC strictly wishes to provide Canamere’s product to the public as a support supplement for everyday wellbeing.

Studies have shown ​​that inflammation is closely linked to depression

One of the biggest producers of inflammation is Chronic Stress. Studies have shown ​​that inflammation is closely linked to depression.

Studies show that inflammation is closely linked to depression

Traditionally it is hypothesised that people who are depressed have a deficiency in specific neurotransmitters (monoamine) in the body. This deficiency leads to low levels of neurotransmitters such as seratonin and norephinephrine in the brain. Besides this there is more and more evidence that supports the notion that some forms of depression may also be linked to ongoing low-grade inflammation in the body.

Studies have linked depression with higher levels of inflammatory markers compared to people who are not depressed. Have a look at this study .

Another new study published in The Journal of Clinical Psychiatry supports the premise that increased inflammation may play a role in depression.

As you may already know – The Miraculous Endocannabinoid System is a major bodily system and is a most recent & significant discovery of modern medical science. Located in all the major organs of the human body, actually mammals, the Endocannabinoid System has been scientifically observed to be a key system that regulates almost every process in the body.

The Endocannabanoid System is closely linked to the regulation of inflammation in the body.

This study reports that systemic and intrathecal administration of cannabidiol (CBD), a major nonpsychoactive component of marijuana, and its modified derivatives significantly suppress chronic inflammatory and neuropathic pain

Meduca cannabinoid supplement
MeducaTM – Safe for women and children

Not having enough cannabinoids for the Endocannabinoid System to perform its function of highly complex regulation can affect your quality of your life lived, as well as the lives of your loved ones.

DISCLAIMER: 4 WAC is an independent distributor for Canamere. Both 4 WAC and Canamere neither agrees nor disagrees, and does not support, endorse or substantiate any claims or indications made in these external references. We only provide it here for educational purposes for those that are interested in learning more. We invite you to do your own research remembering that Canamere’s product is not a drug & is not intended to diagnose, cure, prevent or treat any disease. 4WAC strictly wishes to provide Canamere’s product to the public as a support supplement for everyday wellbeing.

Does THC or CBD cure breast cancer?

The simple answer to the question: “Does THC or CBD cure cancer?” is in a resounding No. Neither of them do.

Following this the questions then arises. “Can either of them help someone with cancer? The answer to this question can not be given until one can establish what a person means by “help”.

Consider the following:

Drinking a glass of water helps for cancer. Taking a walk in fresh air helps for cancer. Do any of those cure cancer? No they don’t. But do they help? Yes they do.

There are cases where THC has been shown to cause problems, like making the cancer grow faster after the body has built up a resistance to THC. Below you will find some studies relating to breast cancer and tumor growth.

When Science Becomes Important

In a study done and published in on March 15, 2005, it was shown that exposure to marijuana either recreationally or medicinally may increase the susceptibility to and/or incidence of breast cancer as well as other cancers that do not express cannabinoid receptors and are resistant to Delta9-THC-induced apoptosis. If science is of importance to you (which it is to me) you can read more on this here: Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response.

Here are some studies that show risks about THC that may be worth looking at:

https://www.ncbi.nlm.nih.gov/pubmed/15026328

https://www.ncbi.nlm.nih.gov/pubmed/12514108

Note the very specific difference between THC or Delta-9-THC and CBD. THC is the psychoactive element in marijuana. CBD is non-psychoactive and has been proven to reduce tumor growth and many other benefits. There seems to be a difference in how different parts of the body react to cancer and cannabis, especially when it comes to breast cancer. When one embarks on this journey, research is imperative because no statement is absolute or specifically 100% correct. My conclusion is that Cannabinoids may help treat the side effects of cancer and cancer treatment.

Other possible effects of cannabinoids may include:

  • Anti-inflammatory activity.
  • Blocking cell growth.
  • Preventing the growth of blood vessels that supply tumors.
  • Antiviral activity.
  • Relieving muscle spasms caused by multiple sclerosis.

Obviously one would like to avoid breast cancer, or any cancer for that matter, altogether. For me the key is to find a balanced way of living. And even more importantly to make sure the environment in your body is managed effectively through thought, belief and habits.

Does THC or CBD cure breast cancer? I believe balance is key to a long and healthy life.
Balance is key!

I found what this man says very interesting. Have a look and see what you think.

https://www.youtube.com/watch?v=GCG1zj3mxOw

The Inside Story of Cannabidoil

What are the benefits of Canabidoil (CBD)? This video is a brilliant analogy of what CBD does to one’s body. After seeing this video on The Inside Story of Cannabidoil you will fully comprehend the effect in a, sort of, layman’s way.

We supply a top quality CBD oil called Meduca™ right here in South Africa. It is a nutritional supplement to assist the body restore its natural balance. To read more about Meduca™ please click here or click here to order now.

Parkinson’s disease and the Endocannabinoid system

The occurrence of Parkinson’s disease in conversations I have lately made me feel like I should put down some information on it on my blog relating to Parkinson’s disease and the Endocannabinoid system. .

Who is affected by Parkinson’s?

Parkinson’s affects 1% of the elderly population. That is quite a significant amount! Age seems to be the most significant factor. A very low percentage of people develop Parkinson’s below the age of 65 years. There are some who believe it is in the genes, i.e. inherited but there is no conclusive evidence that this is the only cause. Conclusive cause is still a mystery. I believe we know exactly what the cause is but that’s just my opinion.

What is Parkinson’s?

Parkinson’s affects the way you move. It happens when there is a problem with certain brain cells. The most interesting thing is that these cells produce Dopamine. Dopamine is a chemical used by the body to send signals to the parts of your brain that controls movement. It causes your muscles to move smoothly and to “follow your instruction”. These nerve cells break down and this is then called Parkinson’s. Once this starts happening you start losing control of not only the way you move but also the way your body follows your instruction.

Can Parkinson’s be cured?

The most debilitating part about Parkinson’s is that it doesn’t go away. It progressively gets worse over time. It happens fairly slowly over many years.

Interestingly, although there are studies that propose to treat Parkinson’s there is hardly any clinically proven new therapies for its cure. Increasing evidence suggests that cannabinoids have a strong influence in the “movement” part of the brain called the basal ganglia. Without getting too technical it basically forms a significant part of the interaction between specific chemicals found in the brain that are responsible for movement.

The difficulty with treating Parkinson’s is because it is difficult to get enough synthetic drug elements to have good tissue penetration, especially in passing the blood brain barrier, without reaching toxic levels.

“Cannabinoid receptors in the brain appear to be intimately involved in the motor control. Cannabinoid CB1 receptors are densely located in the basal ganglia (BG), a forebrain system that integrates cortical information to coordinate motor activity regulating signals. In fact, the administration of plant-derived, synthetic or endogenous cannabinoids produces several effects on motor function. These effects are paralleled to changes in the levels of different neurotransmitters in the BG, including GABA, dopamine and glutamate, all of which are important players in movement control.

Cannabinoid receptors also participate in the etiopathology of movement disorders such as Parkinson’s disease (PD) or Huntington’s disease (HD). In fact, both CB receptors and endocannabinoid levels are altered in the BG of patients with PD and HD and animal models of these diseases. The benefit of cannabinoids in PD or HD is not limited to the symptomatic amelioration, since several publications have revealed interesting neuroprotective and anti-inflammatory effects of these drugs. It has been suggested that cannabinoid modulation may constitute an important component in new therapeutic approaches to the treatment of motor disturbances.”

https://www.intechopen.com/books/cannabinoids-in-health-and-disease/cannabinoids-and-motor-control-of-the-basal-ganglia-therapeutic-potential-in-movement-disorders

It was also found in a study, and of course patented, that cannabinoids are antioxidants and are very useful in treating many oxidation associated diseases. Cannabinoids can function as neuroprotectants and can be used in treating diseases caused by oxidative stress. Very interestingly any of the cannabinoids can be used for this and not particularly THC (which is the psychoactive cannabinoid – the one that causes you to get high).

Here is an abstract from a study done to register a Patent Number US 6630507 B1 with relation to Cannabinoids as antioxidants and neuroprotectants.

Have a look at what was found in this study.

“Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention. A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I) wherein the R group is independently selected from the group consisting of H, CH3, and COCH3.” Meduca is a full plant extract and contains a vast quantity of such nonpsychoactive cannabainoids.

If you haven’t already done so, you can enjoy in depth technical info by clicking here.

Here is more info on studies done in 2015: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404240/

A pretty good multi-faceted look at Cannabis

Here is some great information in a pretty good multi-faceted look at Cannabis in The Cannabis Movie by Spirit Science. Thank you Spirit Science! This is for educational purposes only. We don’t necessarily endorse or agree with it all but it’s a great intro. I’ve been surprised at what I have found since private use of cannabis has been legalised in South Africa.

Meduca is a 100% natural full spectrum plant extract.